摘要
抗 H抗体属于IgM型冷抗体 ,临床鉴定血型时 ,常可引起正反定型不符 ,造成定型困难。在反定型鉴定血型时发现的抗 H抗体中 ,3例患者经血型血清学检测 ,抗体在 37℃、室温、4℃均有活性 ,分析抗体性质为IgM ,提示紧急时刻给AB型患者输血 ,不能盲目输注O型红细胞 ,最好输注同型血。如果没有同型时 ,需输O型红细胞 ,先用盐水离心法配血 ,主侧配血相合时方可发出 ,再用不完全法检测。防止患者有抗 H抗体存在 ,引起输血不良反应。
Anti-H antibody belongs to IgM type cold antibody, which often induces the unconformity of positive and reverse typing and leads to the difficulty in clinical blood typing. Anti-H antibody was found during identification of the counter blood gruop in 3 cases. The antibody was found to be active at 37℃, room temperature and 4℃ when determined by blood gruop serology, and was finally analyzed to be IgM. It is suggested that not to give erythrocytes of O gruop unreasoningly to blood recipient of AB gruop during emergent moment, but instead, to give same type of blood. If there was no same type of blood during urgent events, O type erythrocytes could be employed after being matched by saline centrifuging with host side coincidence and screened by incomplete method. In this case, anti-H antibody leading to adverse-reaction in blood transfusion should be prevented.
出处
《中国实验血液学杂志》
CAS
CSCD
2004年第1期101-102,共2页
Journal of Experimental Hematology
关键词
抗-H抗体
血型鉴定
血型
Anti-H antibody
Blood gruop identification
blood group
