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利什曼素皮内试验用于黑热病疗效评估 被引量:1

THE VALUE OF LDT FOR ASSESSING THE THERAPEUTIC EFFICACY IN KALA-AZAR PATIENTS
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摘要 本文通过对既往137例黑热病患者的LDT测试及10例已愈黑热病人的LDT分析,结果发现LDT在治愈后5年即可阳转,愈后10年以上的原病人大都呈LDT阳性反应(64.13~100%),其反应强度历经51年而不减弱。结合山东省40年来的黑热病个案病例的侦察情况及本次回顾调查结果,并未发现这些原患者在痊愈后有二次真正的感染。初步认为LDT在黑热病的疗效评估和预后监测方面有一定的实用价值。 One hundred and thirty-seven past and 10 recently cured kaia-azar patients were studied by making LDT ( delayed cutaneous hypersensitivity test to LD antigen ) . It was found that LDT could begin to turn positive 5 yr after recovery. Most of the past patients ( 64.13-100% ), who had been cured for more than 10 yr, were LDT positive. And the intensity of the delayed skin hypersensitivity could be maintained for over 51 yr ( in 1 case). A review of the continual records of kala-azar patients kept by Shandong province for 40 yr revealed no repeated infection in the cured patients. It is believed that LDT is of certain value in assessing the efficacy of anti-kala-azar therapy and in the surveillance of cured patients against relapse or reinfection.
出处 《徐州医学院学报》 CAS 1992年第1期23-25,共3页 Acta Academiae Medicinae Xuzhou
关键词 黑热病 疗效 内脏利什曼病 LDT kala-azar LDT therapeutic effectiveness
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