摘要
目的:探讨磁共振弥散成像(DWI)、灌注成像(PWI)及其后处理技术在急性脑梗死,尤其是超早期脑梗死诊断和治疗中的作用。方法:分别应用DWI、PWI和MRA等技术对临床高度怀疑急性脑梗死的患者进行扫描,并根据发病时间进行分组比较,再通过图像后处理技术对所获得图像进行分析。应用上述技术,对1999—2002年间就诊于首钢医院和法国Roger Salengro医院的59例临床诊断为急性脑梗死的患者进行分组和观察。结果:MR平扫T2加权像在发病12 h后才能隐约见到稍高信号的病灶,而DWI、PWI及后处理技术最早可在发病1.5 h发现缺血灶。此外,通过图像后处理可以看到半暗带的情况。结论:DWI、PWI与后处理技术可以明确诊断急性,尤其是超早期脑梗死,同时对治疗方案的制定与调整及评价疗效均有重要意义。
Objective: To detect the use of diffusion-weighted imaging (DWI), perfusion-weighted imaging (PWI) and their post processing technique in the acute cerebral infarction, particularly the effects in the diagnosis and treatment of hyperacute cerebral infarction. Methods: The patients with highly suspected cerebral infarction were scanned with DWI, PWI and MRA, respectively, and compared according to the time of onset, and then the acquired images were processed and analyzed with the post processing technique. With the above technique, 59 patients clinically diagnosed as acute cerebral infarction were divided into 3 groups and observed in Shougang Hospital, Peking University, China and CHRU Roger Salengro Hospital, Lille, France from 1999 to 2002. Results: The lesions with slightly higher density could be seen faintly 12 hours after the onset of the infarction in MR T2-weighted imaging, but they could be seen as early as 1.5 hours in DWI and PWI after the onset of infarction. Besides, the status of the penumbra could be seen with the post processing technique. Conclusions:DWI, PWI and the post processing technique can clearly diagnose acute infarction, particularly the hyperacute cerebral infarction. It also has important significance in making and adjusting treatment protocol as well as evaluating the effectiveness.
出处
《国外医学（脑血管疾病分册）》
2004年第1期41-44,共4页
Foreign Medical Sciences Cerebrovascular Diseases
