摘要
本文采用间接血凝法(IHA)和酶联免疫吸附试验(ELISA)检测了83例脑性瘫痪(下称脑瘫)儿童的血清弓形体抗体,以40例健康儿童为对照。结果发现32.5％脑瘫患儿血清弓形体抗体阳性,显著高于对照组的2.5％(P<0.001)在26例详细调查过围产期因素的病例中,有明确围产期脑损害者弓形体抗体阳性率仅27.1％(3/11),而无明确围产期因素者则高达80％(12/15),两组间差异极显著(P<0.01)。提示弓形体感染可能是部分脑瘫的病因。
Serum antiboy to toxoplasma was determined in 83 cases with cerebral palsy and 40 normal chil-dren by both IHA and ELISA. The results showed that 32.5% of children suffered from cerebral pal-sy with positive antibody to toxoplasma was much higher than 2.5% of control(P<0.001). Through systemic investigation of perinatal factors in 26 cases. the positive rate of toxoplasma antibody in pa-tients with known perinatal brain damage was 27.3% (3/11). significantly lower than 80% (12/15) in ones without identified perinatal factors(P<0.01), Both indicate that some cerebral palsy may be caused by toxoplasmosis.
出处
《现代诊断与治疗》
CAS
1992年第3期259-260,共2页
Modern Diagnosis and Treatment
关键词
脑性瘫痪
弓形体感染
弓形体抗体
Cerebral palsy
Toxoplasmosis
Antibody to toxoplasma
