摘要
选择经纤维胃镜确诊为活动期消化性溃疡,活检证实均伴有不同程度的活动性慢性浅表性胃炎,快速尿素酶试验和组织切片嗜银染色证实幽门螺旋菌阳性的88例,随机分治疗组60例,对照组28例,分别采用雷尼替丁加得乐冲剂或单用雷尼替丁口服,连续服药4周为一疗程,治疗结束后由同一医师行胃镜复查,观察结果:治疗组消化性溃疡愈合率96.6％;HP清除率85％;胃粘膜炎症好转率56.6％;均显著高于对照组。说明西药合用对HP阴性消化性溃疡的疗效明显优于单用雷尼替丁组。
Eighty - eight patients with active peptic ulcer idenfified endoscopically and active chronic superficial gastritis
demonstrated by biopsy, which accompanied by positive HP were divided into two groups at random. Sixty patients were
treated with Ranitidine plus De - Nol po for 4 weeks and twenty - eight as control group which were treated with
Ranitidine 300mp PO. After a treatment course of four wecks, the healing rate of peptic ulcer was 96.6% in the
treatment group and 82.2% in the control grop(P<0.01); the clearing rate of HP was 85% In treatnent group and 7.
1% in the Ranitidine grou(P<0.001); improved rate of gastric mucous membrane inflammation was 56.6% in the
treatment group and 18.0% in the control group(P<0.01). In conclusion: the efficacy of two drugcombination for
treatment of peptic ulcer of positive HP markedly superior to Ramitidine alone.
出处
《现代诊断与治疗》
CAS
1992年第1期12-13,共2页
Modern Diagnosis and Treatment
关键词
幽门螺旋菌
雷尼替丁
溃疡病
Ranitidines. De-Nol
Pepticulcer
Helicobacterpylori(HP)
