期刊文献+

前列腺素E1对慢粒白血病CFU-GMCFU-E及PPC的影响

THE EFFECTS OF PROSTAGLANDIN EI ON CFU-GM,CFU-E,AND PPC IN CHRONIC MYELOID LEUKEMIA
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摘要 慢粒白血病患者周围血的MNC经与前列腺素E1(1×10^(-6)M)预先孵育后,能使CFU-GM、CFU-E及PPC分别增加163.6%,169.0%及216.6%,此结果证实了PGE的阳性造血调节作用. We studied the effects of preincubation of mononuclear cells from the peripheral blood of patients with CML with PGE1 and found that preincubation of the MNCs with PGE1 enhanced the production of CFU-GM,GFU-E and PPC (primary progenitor cells).After preincubation with PGE1,the numbers of colonies increased to 168.6%,169.0%,and 216.6% of the control respectively.These results confirmed the positive control of PGE1 in haemopoiesis.We suggest that PGE may be used as a haemopoietic stimulating agent in some conditions.
出处 《军事医学科学院院刊》 CSCD 北大核心 1989年第5期374-377,共4页 Bulletin of the Academy of Military Medical Sciences
关键词 前列腺素 白血病 CFU-GM PPC prostaglandin E CFU-GM CFU-E PPC
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