摘要
目的 对胡芦巴 Trigonella foenum- graecum种子所含的皂苷成分作深入研究。方法 采用硅胶 H柱色谱 ,干柱色谱等方法从总皂苷中分离纯化皂苷成分并通过 1 3C- NMR,FAB- MS,DEPT等波谱法及部分水解获得次生苷的方法测定了化学结构。结果 从总皂苷中分出两个新皂苷 B和 C,均为薯蓣皂苷元的四糖苷。经测定皂苷 B的化学结构为 :薯蓣皂苷元 - 3- O-α- L -鼠李吡喃糖 (1→ 3) -α- L -鼠李吡喃糖 (1→ 4 ) -β- D -葡萄吡喃糖 (1→ 4 ) -β- D-葡萄吡喃糖苷 ;皂苷 C的结构为薯蓣皂苷元 - 3- O- β- D-葡萄吡喃吡喃糖 (1→ 4 ) - α- L-鼠李吡喃糖 (1→ 4 ) - β- D-葡萄吡喃糖(1→ 4 ) -β- D-葡萄吡喃糖苷。结论 皂苷 B和
Object To do detail investigation of the saponins from the Chinese materia medica Huluba (the seeds of Trigonella foenum graecum L ) Methods The pure saponins from the total saponins were isolated by employing the column chromatography and dry column chromatography of silica gel H Their chemical structures were elucidated by 13 C NMR , FAB MS, DEPT spectroscopic evidence and the results of the fraction hydrolysis of acquiring their secondary glucosides were obtained Results Two new saponins B and C were isolated and both were the glucosides consisted by four molecules of sugar with diosgenin The chemical structure of B is: diosgenin 3 O α L rhamnopyranosyl (1→3) α L rhamnopyranosyl (1→4) β D glucopyranosyl (1→4) β D glucopyranoside And saponin C is: diosgenin 3 O β D glucopyranosyl (1→4) α L rhamnopyranosyl (1→4) β D glucopyranosyl (1→4) β D glucopyranoside Conclusion Saponins B and C are two new ones with four molecules of sugar respectively
出处
《中草药》
CAS
CSCD
北大核心
2004年第2期127-130,共4页
Chinese Traditional and Herbal Drugs
关键词
胡芦巴
皂苷B
皂苷C
Trigonella foenum graecum L
saponin B, saponin C
