期刊文献+

恶性肿瘤抑癌基因IGF-2R的研究进展

暂未订购
导出
摘要 抑癌基因的研究已成为当前头颈恶性肿瘤研究的一个重要方面,本文就抑癌基因IGF-2R的结构和生物学特性,表达与调控,其与细胞增殖及肿瘤的关系进行综述,希望能对该领域的认识及进一步研究提供帮助。
出处 《国外医学(耳鼻咽喉科学分册)》 2004年第1期12-15,共4页 Foreign Medical Sciences(Section of Otolray Ngology Foreign Medical)
  • 相关文献

参考文献15

  • 1李春海 陆士新.一种肿瘤相关因子一类胰岛素生长因子2型在酵母系统中的表达[A]..肿瘤生物学研究进展:第1版[C].北京:军事医学科学出版社,1997.127—130.
  • 2LeRoith D, Baserga R, Helman L, et al. Insulin-like growth factor and cancer.Ann Intern Med. 1995; 122:54-59.
  • 3Hancock MK, Haskins DJ, Sun G, et al. Identification of residues essential for carbohydrate recongnition by the insulin-like growth factor 2/ mannose-6-ohosohate receptor. J Biol Chem. 2002; 277 : 11255-11264.
  • 4Lirmell J, Groeger G, and Bassim HA, et al. Real time kinetics of insulin-like growth factor 2 ( IGF- Ⅱ ) interaction with the IGF- Ⅱ/mannose-6-phosphate receptor: the effects of demain 13 and pH. J Biol Chem. 2001;276: 23986-23991.
  • 5Nykjaer A, Christensen EI, Vorum H, et al. Mannose 6-phosphate/insulin-like growth factor-2 receptor targets the urokinase receptor to lysosomes via a novel binding interaction. J Cell Biol. 1998;141:815-828.
  • 6Scott CD, Weiss J. Soluble insulin-like growth factor 2/mannose-6-phosphate receptor inhibits DNA synthesis in insulin-like growth factor 2 sensitive ceils. J Cell Physiol. 2000; 182 : 62-68.
  • 7Wutz A, Smrzka OW, Schweifer N, et al. Imprinted expression d the Igt2r gene depends on an intronic CpG island. Nature. 1997;389:745-749.
  • 8Szabo PE, Mann JR. Allele-specific expression and total expression levels of imprinted genes during early mouse development: implications for imprinting mechanisms. Genes Dev. 1995 ; 9 : 3097-3108.
  • 9Sotomaru Y, Katsuzawa Y, Hatada I, et al. Unregulated expression of the imprinted genes H19 and Igt2r in mouse uniparental fetuses. J Biol Chem.2002; 277 : 12474-12478.
  • 10Hu JF, Pham J, Dey I, et al. Allele-specific histone acetylation accompanies genomic imprinting of the insulin-like growth factor 2 receptor gene.Endocrinology. 2000; 141:4428--4435.

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部