摘要
目的 了解各种标本来源的产志贺样毒素大肠杆菌(STEC)对常用抗生素的敏感性．方法 采用WHO推荐的K—B法，进行分鉴定菌株对18种抗生素的药物敏感试验，依照NCCLS判定结果．结果 各种来源产志贺样毒素的大肠杆菌共46株，0157型23株，其余为非0157型．全部STEC对复方新诺明耐药，对链霉素耐药率为28．3％(13株)，氨苄西林为30．4％(14株)，红霉素为69．6％(32株)，而且有5株对至少4种以上抗生素产生多重耐药，耐药谱为复方新诺明-链霉素-红霉素-氨苄西林．非O157型STEC耐药菌次为122，而O157型为63．结论 非O157型STEC时抗生素可能较易形成耐药性．
Objective To explore the antibiotic susceptibility of Shiga toxin-producing Escherichia coli (STEC) isolates from all kinds of samples.Methods 18 kinds of antibiotic susceptibility was tested by Kirby-Bauyer protocol recommended by WHO.Results There were total 46 strains STEC to produce Shiga-like toxin. All STEC strains resisted to Sulfamethoxazole timethoprim, and the rate of resistant to Ampicillin, Erythromycin and Streptomycin was respectively (30.4%), (69.6%), (28.3%). 5 isolates resisted to multiple antibiotics. The total resistant number of non-O157 strains were 122, O157 were 63.Conclusion Non-O157 STEC strains might be liable to antibiotic resistance.
出处
《北华大学学报（自然科学版）》
CAS
2004年第1期31-33,共3页
Journal of Beihua University（Natural Science）
关键词
STEC
耐药性
监测
Shiga toxin-producing E.coli
Antibiotic resistance
Supervision
