摘要
目的 探讨暂时性金属内支架治疗贲门失弛缓症对食管动力的影响。方法 2 9例贲门失弛缓症患者在X线透视下置入国产可扩张带膜金属内支架 ,术后 3~ 7d由胃镜取出。治疗前后均测定下食管括约肌 (loweresophagealsphincterLES)静息压、松弛率及食管内 2 4hpH监测。 12名健康人测定LES静息压、松弛率。结果 支架扩张前LES静息压显著高于扩张后 ;扩张前LES松弛率显著高于扩张后 ;扩张后LES静息压和松弛率与健康人相比差异无显著性。扩张后胃食管反流 (GER)率显著高于扩张前。结论 暂时性金属内支架扩张术能显著降低贲门失弛缓症患者的LES压力 。
Objective To explore the effect of achalasia with temporary metal internal stent dilation on esophageal motility.Methods Twenty nine patients with achalasia were undertaken temporary metal internal stent placement under X ray control (stents were of 20 25 mm in diameters). After stent dilation 3 7 days, the stents were removed by endoscopy. We measured the lower esophageal sphincter (LES) residual pressure and carried out 24h pH value monitor on the patients, and only LES pressure with relaxation rate for 12 healthy subjects (HS). Results LES residual pressure before stent dilation were markedly higher than that after stent dilation ( P <0.01). LES relaxation rates were significantly different between prestent dilation and poststent dilation ( P <0.01). The frequency of gastroesophageal reflux (GER) after stent dilation was markedly higher than that before stent dilation ( P <0.01). Residual pressure and relaxation rate showed no significant difference between HS and after stent dilation ones ( P >0.05).Conclusions Temporary metal internal stent dilation shows LES pressure and higher rate of GER for achalasia
出处
《介入放射学杂志》
CSCD
2003年第2期124-125,共2页
Journal of Interventional Radiology