摘要
目的 探讨老年高血压病患者高胰岛素血症与血糖、血清脂质水平之间的关系。方法 对 78例老年高血压病患者(观察组 )及 60例老年对照组 ,进行了血清甘油三酯 (TG)、总胆固醇 (TC)、高密度脂蛋白胆固醇 (HDL -C)、低密度脂蛋白胆固醇(LDL -C)、载脂蛋白AI(ApoAI)、载脂蛋白B(ApoB)、脂蛋白 (a) [Lpo (a) ]、空腹血糖 (FPG)及胰岛素 (INS)的测定。 结果 观察组血清TG、LDL -C、Lpo(a)、INS、FPG含量明显高于对照组 ;观察组血清HDL -C、ApoAI水平和胰岛素敏感性指数 (ISI)明显低于对照组。结论 老年高血压病患者胰岛素、血脂和血糖代谢异常的共存是该病发生、发展的危险因素 ,也是心、脑血管疾病的危险因素 ,故在降压治疗的同时 ,应考虑纠正其胰岛素、糖及脂代谢的异常。
Objective To evaluate the relationship between the plasmatic level of glucose and lipid in old patients with hypertension. Method The plasmatic levels of triglyceride(TG),total cholesterol(TC),high-density lipoprotein cholesterol(HDL-C),low-density lipoprotein cholesterol(LDL-C),apolipoprotein A-I(Apo-AI),apolipoprotein B(Apo-B), lipoprotein(a),fasting plasma glucose(FPG) and insulin were detected in 78 old patients with hypertension and 60 normal controls. Results The plasmatic levels of TG, lipoprotein(a), FPG and insulin in patients with hypertension were higher than those in controls. The plasmatic levels of HDL-C, Apo A-I and insulin sensitivity index(ISI) in patients with hypertension were lower than those in controls. Conclusion The abnormal metabolisms of plasmatic glucose,lipid and insulin are the risk factors of hypertension, cardiovascular and cerebrovascular disease in old patients. It's necessary to correct those abnormal metabolisms while controlling bleed pressure.
出处
《实用全科医学》
2004年第1期43-44,共2页
Applied Journal Of General Practice
