摘要
目的 :观察利多卡因与氨茶碱联合用药对支气管哮喘患者的疗效。方法 :对 78例支气管哮喘患者予以分组 ,分治疗组 38例 ,给予氨茶碱与利多卡因联合静脉滴注 ,利多卡因用量 1.5mg/kg ,氨茶硷用量 4~ 6mg/kg。对照组 4 0例 ,给予氨茶碱静脉滴注 ,氨茶碱用量 4~ 6mg/kg。两组患者均接受常规抗哮喘治疗。根据疗效判断 ,观察两组患者近愈、显效、有效、无效、有效率、复发率及副反应发生率。结果 :治疗组有效率 97.4 % ,复发率 2 6 .0 % ,副反应发生率 5 .0 % ,对照组有效率 85 .0 % ,复发率 4 7.5 % ,副反应发生率 30 % ,两组比较有显著差异 (P <0 .0 5 )。结论 :本研究表明 :氨茶碱与利多卡因联合静脉用药对支气管哮喘患者有明显疗效 ,既可增强利多卡因与氨茶碱使用的安全性 ,降低两药副反应的发生率 ,又可以降低支气管哮喘患者对激素治疗的依赖性 ,可望成为一个皮质激素的替代品。
Objective: To observe the treatment effects of bronchus asthma with Anchajian and Lidocaine. Method: Seventy-eight bronchus asthma cases were divided into two groups, the treatment group of 38 patients received the unite Anchajian with lidocaine vein drop dot ,the use dose of Anchajian is 4~6mg/kg,the use dose of lidocaine is 1.5mg/kg.The control group of forty patients received Anchajian vein drop dot, the use dose is 4~6mg/kg. Observe the obvious effect of treatment, the near period cures, validity, invalid, validity rate and relapse rate, the rate of vice-reaction occurrence. Result: The validity rate of treatment group was 97.4%, the relapse rate was 26.0%, the rate of vice-reaction occurrence was 5%. The validity rate of eorctrol group was 85.0%, the ralapse rate was 47.5%, the rate of vice-reaction occurrence was 30%.There is significant difference between the two groups (p<0.05).Conclusion: The research enunciated that association with the vine use the medicine Anchajian and lidocaine is effective to the patients of bronchus asthma. Not only to enhance the safety of use the two medicines, but also to lower the patients dependence to the treatment of hormone, it may become a substitute of hormone.
出处
《河北医学》
CAS
2003年第12期1061-1062,共2页
Hebei Medicine