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帕罗西汀、西沙必利治疗功能性消化不良的疗效观察 被引量:2

Efficacy of Paroxetine and Prepulsid in Treating Functional Dyspepsia
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摘要 目的 观察帕罗西汀、西沙必利联合治疗功能性消化不良 (FD)的疗效。 方法 5 6例FD患者随机分为两组 ,A组 2 8例予以西沙必利 5mg ,3次 /d ,帕罗西汀 2 0mg ,1次 /d。B组 2 8例予以西沙必利 5mg ,3次 /d ,疗程均为四周。 结果 A组显效率 5 3 6 % ,有效率 35 7% ,总有效率 89 3%。B组显效率 2 1 4 % ,有效率39 3% ,总有效率 6 0 7% ,两组总有效率差异显著 (P <0 0 1)。 结论  帕罗西汀、西沙必利联合治疗FD优于单用西沙必利。 Objective To investigate the efficacy of treating functional dyspepsia (FD) with paroxetine and prepulsid.Methods 56 cases of FD were divided into two groups randomly. Group A 28 cases were given Prepulsid 5 mg, tid, Paroxetine 20 mg, qd, Group B 28 cases were given Prepulsid 5 mg, tid. The course was four weeks.Results The responseive rate of A group was 53.6%, The effective rate of group A was 35.7%. The total effective rate was 89.3%. The responseive rate of B group was 21.4%. The effective rate of B group was 39.3% The total effective rate was 60.7%. There was significant difference in the total effective rate between the two groups(P<0.01).Conclusion The combined paroxetine and prepulsid treatment is better than prepulsid alone in the treatment of FD.
作者 杨春明
出处 《医药论坛杂志》 2003年第24期24-25,27,共3页 Journal of Medical Forum
关键词 功能性消化不良 帕罗西汀 西沙必利 药物治疗 精神心理因素 functional dyspepsia psychological factors antidepressants
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