摘要
目的 :探讨慢性心力衰竭患者血清尿酸浓度变化规律及其临床意义。方法 :比较 80例不同病因、不同心功能状态下的血尿酸浓度以及治疗前后其浓度的变化。结果 :慢性心力衰竭患者血尿酸浓度随心功能的恶化而升高 ,Ⅱ、Ⅲ、Ⅳ级心力衰竭血尿酸浓度分别为 2 95 .6± 44 .1μmol/L ,3 43 .5± 14 4.9μmol/L ,5 5 6.7± 197.3 μmol/L。治疗前 ,血尿酸浓度为 5 76.4± 98.7μmol/L(LVEF≤ 0 .3 0 ) ,3 5 6.8± 72 .1μmol/L(LVEF >0 .3 0 ) ,治疗后 ,血尿酸浓度分别为 45 6.4± 87.5 μmol/L ,3 2 8.7± 65 .1μmol/L ,与治疗前相比 ,P <0 .0 1。结论 :心力衰竭患者血尿酸浓度增高 ,与心力衰竭的严重程度相关 ,治疗后 。
Objective To assess clinical significance of changes of serum uric acid in patients with chronic heart failure. Methods Eighty patients with different causes and cardiac function were compared the concentration of serum uric acid and its changes after treatment. Results The concentrations of serum uric acid in chronic heart failure patients in NYHA functional II-IV grade were 295.6±44.1μmol/L, 343.5±144.9μmol/L and 556.7±197.3μmol/L. After treatment the concentrations of serum uric acid changed from 576.4±98.7μmol/L (LVEF≤0.30) and 356.8±72.1 μmol/L (LVEF>0.30) to 456.4±87.5μmol/L and 328.7±65.1μmol/L respectively (P<0.01). Conclusion The concentration of serum uric acid is increased in chronic heart failure and it is associated with severity of heart failure.
出处
《实用诊断与治疗杂志》
2004年第1期4-5,共2页
Journal of Practical Diagnosis and Therapy
关键词
尿酸
慢性心力衰竭
Uric acid
chronic heart failure
