摘要
目的 探讨小儿原发性肾毛霉菌病的临床特点。 方法 对 3例小儿原发性肾毛霉菌病的症状、体征、CT和IVU表现、手术情况等进行分析 ,结合文献讨论其临床特点。 结果 1例新生儿患者无明显症状 ,表现为肾区肿块 ;另 2例均有高热、腰痛、血尿、肾脏肿大和肾区压叩痛。CT可见肾内多个低密度病灶。 1例尿液镜检见毛霉菌。 3例均行肾脏切除术加两性霉素B治疗 ,诊断经病理证实。 结论 毛霉菌病单独累及肾脏者罕见 ,具有不同于全身性毛霉菌病的临床特点。早期诊断、积极手术并抗真菌治疗可改善预后。
Objective To investigate the clinical characteristics of isolated renal mucormycosis in children. Methods The clinical manifestations,CT,IVU and surgical findings of 3 children with isolated renal mucormycosis were analyzed. Results A three-month newborn presented asymptomatically except for renal mass.The other two children had fever,lumbar pain,hematuria,renal enlargement and tenderness.CT scan showed multiple low density foci in the kidneys.All of the three children underwent nephrectomy and systemic amphotericin B treatment,and the diagnoses were confirmed by pathological examination. Conclusions Isolated renal mucormycosis is a rare fungal infection without predisposing factors,and its clinical characteristics are different from the usual systemic mucormycosis.Early diagnosis,nephrectomy and systemic amphotericin B treatment are necessary for improving the prognosis.
出处
《中华泌尿外科杂志》
CAS
CSCD
北大核心
2003年第7期437-438,共2页
Chinese Journal of Urology
