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PC12细胞凋亡及其细胞膜表面超微结构的原子力显微镜形态学观察 被引量:4

Topographical observation of apoptosis and membrane surface ultrastructure of PC12 cells
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摘要 本文采用原子力显微镜 (AFM)对PC12细胞的凋亡及其膜表面超微结构进行了实验研究 ,研究表明AFM可直接观察PC12细胞的生长情况 ,凋亡细胞膜发生皱缩、凹陷 ,并形成微绒毛消失的凋亡小体等现象。 Apoptosis and membrane surface ultrastructure of PC12 cells were investigated by atomic force microscopy. We found that AFM could be utilized to directly observe the growth and apoptosis phenomena of PC12 cells. Difference of ultrastructure between normal cell and apoptotic particles was found. AFM could be used as a novel tool for researches on cell apoptosis
出处 《电子显微学报》 CAS CSCD 北大核心 2003年第4期311-314,共4页 Journal of Chinese Electron Microscopy Society
基金 国家自然科学基金资助项目 (No .60 2 780 14 ) 国家自然科学基金重点项目 (No .3 0 2 3 0 3 5 0 ) 国家重点基础研究发展规划项目("973")基金资助项目 (No .2 0 0 1CB5 10 10 1) 教育部科技重点项目 (No.0 0 12 4)
关键词 PC12细胞 细胞凋亡 超微结构 原子力显微镜 细胞膜 细胞培养 apoptosis PC12 cells ultrastructure atomic force microscopy (AFM)
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同被引文献61

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