摘要
目的探讨重复经颅磁刺激对帕金森病患者的治疗作用。方法采用重复经颅磁刺激方法对8例帕金森病患者进行治疗,另选择7例帕金森病患者作为对照。采用改进的H&Y(HoehnandYahr)评分标准、SchwabandEngland日常生活能力评分量表以及帕金森病症状评分量表(UPDRS)进行疗效评估。结果8例接受重复经颅磁刺激治疗的患者,于治疗第3、6和9个月时进行H&Y评分和UPDRS评分,与治疗前相比,这两种评分均明显下降(P<0.05),而SchwabandEngland日常生活能力评分则明显提高,治疗前后相比差异具有显著性意义(P<0.05);对照组治疗前后相比差异无显著性意义(P>0.05)。结论重复经颅磁刺激有助于缓解帕金森病患者的症状。
Objective To study the therapeutic effect of repetitive transcranial magnetic stimulation (R-TMS) on Parkinson's disease (PD). Methods Eight patients with PD were performed R-TMS therapy and other 7 patients were enrolled as control. The modified Hoehn and Yahr (H&Y) Staging Scale, Schwab and England Activities of Daily Life (ADL) Scale and Unified Parkinson's Disease Rating Scale (UPDRS) were adopted to assess the therapeutic effect. Results In all of the 8 patients treated with R-TMS, the result of H&Y Staging Scale and UPDRS decreased significantly in 3, 6 and 9 months after treatment, while their Schwab and England ADL scores remarkably increased, compared with control, the difference was statistically significant (P < 0.05). Conclusion The treatment of R-TMS is beneficial for relieving symptoms in PD patients.