期刊文献+

重复经颅磁刺激治疗帕金森病 被引量:6

Repetitive transcranial magnetic stimulation in Parkinson's disease
原文传递
导出
摘要 目的探讨重复经颅磁刺激对帕金森病患者的治疗作用。方法采用重复经颅磁刺激方法对8例帕金森病患者进行治疗,另选择7例帕金森病患者作为对照。采用改进的H&Y(HoehnandYahr)评分标准、SchwabandEngland日常生活能力评分量表以及帕金森病症状评分量表(UPDRS)进行疗效评估。结果8例接受重复经颅磁刺激治疗的患者,于治疗第3、6和9个月时进行H&Y评分和UPDRS评分,与治疗前相比,这两种评分均明显下降(P<0.05),而SchwabandEngland日常生活能力评分则明显提高,治疗前后相比差异具有显著性意义(P<0.05);对照组治疗前后相比差异无显著性意义(P>0.05)。结论重复经颅磁刺激有助于缓解帕金森病患者的症状。 Objective To study the therapeutic effect of repetitive transcranial magnetic stimulation (R-TMS) on Parkinson's disease (PD). Methods Eight patients with PD were performed R-TMS therapy and other 7 patients were enrolled as control. The modified Hoehn and Yahr (H&Y) Staging Scale, Schwab and England Activities of Daily Life (ADL) Scale and Unified Parkinson's Disease Rating Scale (UPDRS) were adopted to assess the therapeutic effect. Results In all of the 8 patients treated with R-TMS, the result of H&Y Staging Scale and UPDRS decreased significantly in 3, 6 and 9 months after treatment, while their Schwab and England ADL scores remarkably increased, compared with control, the difference was statistically significant (P < 0.05). Conclusion The treatment of R-TMS is beneficial for relieving symptoms in PD patients.
出处 《现代神经疾病杂志》 2003年第4期228-230,共3页
关键词 重复经颅磁刺激 治疗 帕金森病 电磁场 物理刺激 日常生活能力 Parkinson disease Electromagnetic fields Physical stimulation Activities of daily living
  • 相关文献

参考文献19

  • 1[1]Barker AT, Jalinous R, Freeston IL. Non-invasive magnetic stimulation of human motor cortex. Lancet, 1985, 1:1106-1107.
  • 2[2]Barker AT, Freeston IL, Jalinous R, et al. Magnetic stimulation of the human brain and peripheral nervous system: an introduction and the results of an initial clinical evaluation. Neurosurgery, 1987, 20:100-109.
  • 3[3]Bridgers SL, Delaney RC. Transcranial magnetic stimulation: an assessment of cognitive and other cerebral effects. Neurology, 1989,39:417-419.
  • 4[4]Kandler RH, Jarratt JA, Sagar H J, et al. Abnormalities of central motor conduction in Parkinson's disease. J Neurol Sci, 1990, 100:94-97.
  • 5[5]Eisen A, Siejka S, Schulzer M, et al. Age-dependent decline in motor evoked potential (MEP) amplitude: with a comment on changes in Parkinson's disease. Electroencephalogr Clin Neurophysiol, 1991,81:209-215.
  • 6[6]Cantello R, Gianelli M, Bettucci D, et al. Parkinson's disease rigidity: magnetic motor evoked potentials in a small hand muscle. Neurology, 1991, 41:1449-1456.
  • 7[7]Hallett M, Cohen LG, Bierner SM. Studies of sensory and motor cortex physiology: with observations on akinesia in Parkinson's disase.Electroencephalogr Clin Neurophysiol Suppl, 1991, 43:76-85.
  • 8[8]Valzania F, Quatrale R, Strafella AP, et al. Pattern of motor evoked response to repetitive transcranial magnetic stimulation. Electroencephalogr Clin Neurophysiol, 1994, 93:312-317.
  • 9[9]Valls-Sole J, Pascual-Leone A, Brasil-Neto JP, et al. Abnormal facilitation of the response to transcramial magnetic stimulation in patients with Parkinson's disease. Neurology, 1994, 44:735-741.
  • 10[10]Pascual-Leone A, Valls-Sole J, Brasil-Neto JP, et al. Akinesia in Parkinson's disease. Ⅰ. Shortening of simple reaction time with focal, single-pulse transcranial magnetic stimulation. Neurology, 1994,44:884-891.

同被引文献135

引证文献6

二级引证文献62

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部