摘要
目的 :研究清解宁对绵羊红细胞 (SRBC)免疫小鼠细胞因子的影响。方法 :用SRBC免疫小鼠 ,以巨噬细胞NO-2 释放法检测IFN γ水平 ,胸腺细胞法检测IL 1水平 ,丝裂原激活的淋巴母细胞法检测IL 2水平 ,观察清解宁对小鼠IL 1、IFN γ、IL 2的影响。结果 :清解宁能明显抑制免疫小鼠IL 1、IFN γ、IL 2的分泌。结论 :清解宁免疫抑制作用可能与其抑制免疫细胞分泌IL 1、IFN γ、IL
AIM: To investigate the effect of Qingjiening(QJN) on cytokines in sheep red blood cell(SRBC)-immunized mice. METHODS: After immunization of mice with SRBC, the effect of QJN o n IL-1、IFN-γ、IL-2 in mice was observed, the IFN-γ level was measured by macrophage NO - 2-release assay, the IL-1 level was measured by thymocyte a ssay, the IL-2 level was measured by mitogen activated lymphocytoblast assay. RESULTS: QJN can significantly inhibit mice to secrete IL-1、IFN- γ and IL-2. CONCLUSION: The immunosuppressive activity of QJN may be associate d with inhibition of immunocyte to secret IL-1、IFN-γ and IL-2.
出处
《中成药》
CAS
CSCD
北大核心
2004年第1期48-51,共4页
Chinese Traditional Patent Medicine
