摘要
目的 评价腰穿脑脊液生理盐水置换术防治蛛网膜下腔出血 (SAH)并发脑血管痉挛 (CVS)及正常压力脑积水 (NPH)的疗效及安全性。方法 将符合入选标准的患者分为实验组 (4 6 1例 )和对照组 (388例 ) ,实验组给予反复腰穿、椎管内分次注入生理盐水 30～ 6 0 m l进行脑脊液置换 ,对照组常规治疗。观察两组患者临床症状及头颅 CT变化 ,评价其疗效。结果 CVS和 NPH发生率分别为实验组 6 .9% (32例 )、4 .3% (2 0例 ) ,对照组17.2 % (6 7例 )、9.5 % (36例 ) ,总有效率实验组 94 .8% ,对照组 82 .5 %。结论 该方法在防治 SAH并发
Objective To estimate the curative effect and security of lumbar puncture and cerebral spinal fluid replacement with 0.9% NaCl to prevent and treat cerebralvascular spasm(CVS)and normal pressure hydrocephalus(NPH)in patients with subarachnoid hemorrhage(SAH).Method To divide the patient of SAH which fill the criteria into two groups,experimental group(461 cases)and control group(388 cases).Repeated lumbar puncture and cerebral spinal fluid replacement with 0.9% NaCl was performed to the patients of experimental group,30～60ml CSF was replaced every time.Routine treatment but without CSF replacement in the control group.Clinical manifestation and changes in head CT was observed and the curative effect was estimated.Result The rates of CVS and NPH were 6.9%(32 cases)and 4.3%(20 cases)individually in experimental group,17.2%(67 cases) and 9.5%(36 cases)individually in control group.The efficiency rates were 94.8% in experimental group and 82.5% in control group(P<0.01).Clonclusions The therapy of CSF replacement is effective on prevention and treatment in patients with SAH companied with CVS and NPH.
出处
《山东医药》
CAS
北大核心
2004年第1期12-13,共2页
Shandong Medical Journal
关键词
腰穿脑脊液生理盐水置换术
蛛网膜下腔出血
并发症
脑血管痉挛
脑积水
预防
治疗
Subarachnoid hemorrhage Cerbralvascular spasm Normal pressure hydrocephalus Lumbar puncture and cerebral spinal fluid replacement
