摘要
目的:观察苦参素注射液应用于慢性乙型肝炎治疗的抗肝纤维化作用。方法:选取慢性乙型肝炎患者200例,随机分成两组,治疗组100例,在一般保肝治疗基础上,加用苦参素注射液静脉滴注,600mg/次,1次/日,疗程1月;对照组100例,应用一般保肝治疗,疗程1月。两组均于治疗前后观察症状、体征、肝功能及血清透明质酸(HA)、层粘蛋白(LN)、IV型胶原(CL-IV)等肝纤维化指标变化。统计学处理。结果:两组患者的症状、体征均好转,肝功能改善,治疗组优于对照组。结论:苦参素注射液应用于慢性乙型肝炎治疗,不仅具有较好的保肝作用,且抗纤维化作用效果显著。
Objective: To observe the anti - fibrosis effects of injection of Kurarinone in treating chronic hepatitis B. Methods: 200 cases of chronic hepatitis B patients were selected and divided at random into two groups. 100 cases in the treatment group were treated with intravenous drip of Kurarinone injection on the basis of general liver - protecting treatment, 600mg each time, once a day for one course of treatment of a month; 100 cases in the control group were treated with the common liver - protecting therapy for a month as one course of treatment. The fibrosis index changes before and after the treatment were observed both in the treatment and control groups like symptom, signs, liver functions, HA, LN, CL - IV. Results: Patients in both groups obtain improvement of symptoms, signs and liver functions, and the treatment group was better than the control group. Conclusion: Treatment of chronic hepatitis B with Kurarinone injection not only has better liver - protecting effects, but also marked anti - fibrosis effects.
出处
《陕西中医学院学报》
2004年第1期63-64,共2页
Journal of Shaanxi College of Traditional Chinese Medicine
关键词
苦参素
慢性乙型肝炎
治疗
抗纤维化作用
chronic hepatitis B
Kurarinone injection
therapeutic effects
