摘要
运用建立起来的酶联免疫吸附试验对80名胃镜确诊胃炎及消化性溃疡患者的血清中抗幽门螺旋菌(Helicobacter pylori)IgG、IgA IgM进行了检测。结果表明,抗H.pylori IgG、IgA都可作为H.pylori感染的指标,但前者敏感性较好(92.0%),后者特异性较高(94.4%);抗H.pyloriIgM升高和降低与H.pylori感染无明显关系。抗H.pylori IgG、IgA水平与H.pylori感染程度无明显相关关系。正常人群中抗H.pylori IgG的50岁以上阳性率逐渐下降,而IgA升高。
Sera from 80 patients suffering from gastritis and/or digestive ulcer were examined for IgG, IgA and IgM to Helicobacter pylori by enzyme-linked immunosorbent assay (ELISA). Anti-H. pylori IgG and IgA in serum could be used for diagnosis of H. pylori infection, but the former had good sensitivity (92.0%) and the latter had a great specificity (94.4%). Serum anti-H, pylori IgM level was not associated with H. pylori infection. There were no remarkable relationship between H. pylori infection degree arid levels of anti-H, pylori IgG IgA. The positive percentage of anti-H, pylori IgG of health population deceased after 50 years old but the anti-H, pylori IgA increased.
出处
《微生物学通报》
CAS
CSCD
北大核心
1992年第4期217-221,共5页
Microbiology China
