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冷暴露大鼠红细胞膜钠泵与细胞内钠/钾比值间相互关系的探讨

Study on the Correlation between Na Pump and Na/K in Red Blood Cells Membrane for Cold Expoured Rats
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摘要 研究了大鼠冷暴露1~6周,红细胞膜(Na,K)-ATPase及细胞内Na的变化,结果表明在整个冷暴露期间,红细胞膜(Na,K)-ATPase酸及细胞内Na/K比值均显著高于对照组(P<0.05),红细胞膜(Na,K)-ATPase酶与细胞内Na比值间有明显的相关性(γ=0.917),提示借助于钠泵的离子运输是冷适应细胞产热的主要机制。 In this study, the sodium and potassium adenosine triphatase (Na, K-ATPase) in everythrocyte, and electrolyte content of sodium and potassium in red blood cells were measured for rats exposed to cold from 1 to 6 weeks. The results show that ATPase activtise in the erythrocyte membrane, and sodium, potassium in red blood cells were significantly higher than that of control group at all the process (P < 0. 05). An apparent correlation was noted between the Na, K-ATPase activities in the erythrocyte membrane and Na/K in blood cells (γ= 0. 917). It indicats that Na transport by means of cell membrane Na pump is a major-mechanism for increasing the thermoregulatory nonshivering thermogenesis in the rat.
出处 《广东微量元素科学》 CAS 1995年第6期16-19,共4页 Trace Elements Science
关键词 冷暴露 大鼠 红细胞膜 钠离子 钾离子 冷适应 离子运输 Cold expoure,Cold adaptation,Erytbrocyte membrane.
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