摘要
本文报告29例中线恶性网状细胞增多症,着重对临床、病理形态及,免疫组化观察进行探讨.病理诊断依据是:1、有显著的坏死.2、炎性浸润及异形淋巴细胞(ALC)浸润,并浸润粘膜上皮及缸管壁.3、ALC 的形态分大、中、小3型,数量随临床分期而变化.免疫组化标记结果,病变组织中 ALC 呈 UCHL_1,LCA 膜阳性反应,而 K、λ、Mac_(387)、Lysozymc 均呈阴性反应,提示是 T 细胞来源的恶性淋巴瘤.
In this paper 29 cases of midline malignant reticulosis (MMR) are reported.The enphasis is put on the clinical,histopathologic and immunohistochcmical observation.The pathologic diagnosis was based on the following:1.the significant necrobiosis,2.The infiltration of inflammation and atypical lymphoid cell (ALC),3.the infiltration of ALC onto the mucosa of epithelial and vascular wall.Accordign to the size,ALC were divided into three subtypes:the large,intermediate and small groups.Their amount of ALC changed with the clinical stage.The result of immunohistochemical study showed that UCHL and LCA reactions were positive,while K,λ,Mac_(387)and lysozyme reaction negatiae.It indicates that ALC of MMR belong to one kind of T-cell origin lymphoma.
出处
《皖南医学院学报》
CAS
1992年第3期181-183,共3页
Journal of Wannan Medical College
关键词
中线恶性
网状细胞
增多症
淋巴瘤
reticulosis
malignant midline
granuloma
lethal midline
lymphoma
