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新生儿肺的神经支配——组织化学和免疫组织化学研究

THE INNERVATION OF THE NEONATE LUNG:HISTOCHEMICAL AND IMMUNOHISTOCHEMICAL STUDY
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摘要 本文用神经组化和免疫组化方法,对32例新生儿肺的神经分布进行了系统地观察,并讨论其分布特点.实验表明,新生儿肺受胆碱能、肾上腺素能和血管活性肠肽(VIP)能神经支配.前两种神经纤维从支气管一直追踪到终末细支气管.VIP 能神经纤维布于肺内支气管平滑肌和腺体,分布密度与胆碱能神经纤维大致相同,但远比肾上腺素能神经纤维丰富.新生儿肺内,胆碱能神经节得到证实,但未观察到肾上腺素能和 VIP 能神经节. Using neurohistochemical and immunohistochemical methods,we studied the innervation of 32 neonate lungs.It was found that besides adrenergic and cholinergic innervation,there was also vasoactive intestinal polypeptidergic (VIP) innervation in the neonate lungs,Cholinergic and adrenergic nerve fibers were found to run from the bronchi to terminal bronchioles.VIP like immunoreactive nerve fibers supplied to the bronchial muscle and glands.In the bronchial muscle and glands,the density of VIP like immunoreactive nerve fibers was similar to that of cholinergic nerve fibers,and much more abundant than that of adrenergic nerve fibers.In the neonate lungs,cholinergic ganglia were demonstrated,but no adrenergic ganglion or VIP immunoreactive positive ganglion was observed.In present study the innervation of the neonate lungs is discussed.
出处 《皖南医学院学报》 CAS 1992年第3期160-162,共3页 Journal of Wannan Medical College
关键词 神经纤维 新生儿 神经支配 lung adrenergic fibers cholinergic fibers vasoactive intestimal peptide nerve fibers newborn
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参考文献3

  • 1A. Laitinen,M. Partanen,A. Hervonen,M. Pelto-Huikko,L. A. Laitinen. VIP like immunoreactive nerves in human respiratory tract[J] 1985,Histochemistry(4):313~319
  • 2M. Partanen,A. Laitinen,A. Hervonen,M. Toivanen,L. A. Laitinen. Catecholamine- and acetylcholinesterase-containing nerves in human lower respiratory tract[J] 1982,Histochemistry(2):175~188
  • 3Dr. Richard D. Dey,W. Allen Shannon,Sami I. Said. Localization of VIP-immunoreactive nerves in airways and pulmonary vessels of dogs, cats, and human subjects[J] 1981,Cell and Tissue Research(2):231~238

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