摘要
目的:观察甲羟孕酮合并化疗对中老年晚期肺癌患者疼痛、情绪状态、睡眠质量等生活质量因素的改善。方法:93例中老年晚期肺癌患者随机分为甲羟孕酮合并化疗组(甲羟孕酮组)47例及单独化疗组46例,对两组进行生活质量分析比较。结果:甲羟孕酮组与单独化疗组比较,疼痛缓解、体质量、生活质量评分有明显提高,统计学处理均有显著性意义(z值分别为4.324,6.824,5.853,均P<0.01)。结论:甲羟孕酮能明显控制癌痛,增加患者体重,改善患者生活质量。
AIM:To observe the effect of medroxyprogesterone acetate combined with chemotherapy for improving pain, emotional state, sleep quality and other factors of quality of life(QOL)in middle age and elderly patients with late lung cancer. METHODS:Ninety three patients with late lung cancer were randomly divided into combined treatment group(medroxyprogesterone acetate plus chemotherapy,n=47)and chemotherapy group(n=46).QOL was compared between the two groups. RESULTS:The rate of pain remission, body mass index(BMI) and QOL in the combined treatment group score were obviously higher than those in chemotherapy group. There were significant difference in statistics(z= 4.324,6.824 and 5.853,P< 0.01) CONCLUSION:Medroxyprogesterone acetate plays an effective role in controlling cancer pain, increasing BMI and improving QOL in patients.
出处
《中国临床康复》
CSCD
2003年第32期4362-4363,共2页
Chinese Journal of Clinical Rehabilitation
