摘要
目的 分析本院近 3年来铜绿假单胞菌医院感染分布及其对不同类型抗生素的耐药情况。方法 对本院各病房送检的痰、尿、分泌物等标本进行细菌培养 ,并采用K B法对头孢菌素类、氨基糖甙类等 1 1种抗生素进行药物最低抑菌浓度分析。结果 痰标本中铜绿假单胞菌分离率为 1 0 .8% ,分泌物中为 1 3.6 % ,菌株的 2 1 .3%分布在重症监护病房 ,1 6 .7%分布在烧伤病房 ;抗生素耐药率分别为头孢唑啉 96 .0 %、头孢哌酮 2 4 .3%、头孢他啶 8.9%、环丙沙星 2 1 .8%、庆大霉素 37.8%等。结论 铜绿假单胞菌仍是本院细菌感染的主要致病菌之一 ,主要发生在免疫力低下的危重患者中 ,且对多种不同类型的抗生素耐药 。
Objective To investigate pseudomonas aeruginosa(P.aeruginosa) nosocomial distribution in our hospital and the susceptibility to different antimicrobial agents.Methods Sptutum,urine,pus and other samples from different wards were cultured for bacterium,and antibiotic susceptibility was studied by K B method.Results 10.8%of P.aeruginosa was found from sputum,and 13.6% from secretion.21.3%of P.aeruginosa was isolated in ICU and 16.7% in burn ward.Antibiotic resistant rates was cefzolin 96.0%,cefperazone 24.3%,ceftazidime 8.9%,ciprofloxacin 21.8%,gentamycin 37.8%,respectively.Conclusion P.aeruginosa is still a major pathogenic bacterium in our hospital,mainly existing in immuno compromised elder patients,with resistance to a variety of antimicrobial agents.Third generation cephalosporin and amikacin show better anti bacterium activity.
出处
《重庆医学》
CAS
CSCD
2003年第12期1627-1628,共2页
Chongqing medicine
关键词
铜绿假单胞菌
医院感染
抗生素类
耐药性
pseudomonas
nosocomial infection
antibiotics
drug resistance
