摘要
目的 :探讨影响更年期妇女抑郁症状发生的因素。方法 :采用随机整群抽样方法对长春市三个城区中 939例 45～ 5 5周岁妇女用自评抑郁量表 ( SDS)及抑郁状态问卷 ( DSI)进行抑郁症状的评价及生物、心理、社会因素的流行病学调查 ;采用病例对照研究方法 ,应用放射免疫测定法对有更年期抑郁症状组 ( 组 )妇女、更年期正常对照组 ( 组 )及生育年龄正常对照组 ( 组 )妇女各 30例行血清雌二醇 ( E2 )水平测定。结果 :更年期妇女抑郁症状发生率为 32 .0 6%, 组及 组的 E2 水平均比 组降低 ( P<0 .0 5 ) ; 组血清 E2 水平下降更明显 ,与 组比较差异亦有显著性 ;抑郁症状发生与是否有精神心理症状、血管舒缩症状、有无意外生活事件及年龄大小呈正相关关系 ;与家庭月收入、爱人下岗后是否就业、夫妻感情好坏、对生活是否满意、对自己评价的高低、遇到烦恼淡忘它的时间的长短、是否参加社团组织活动、遇到烦恼是否有家庭或社会的帮助等因素成负相关关系。结论 :更年期抑郁症状发生与 E2 的减少 ,某些躯体、社会、心理因素有关。缓解更年期妇女抑郁症状可考虑应用激素替代疗法。除药物治疗之外 。
Objective: To analyze the factors that have effects on the depression symptom of climacteric women.Methods:Random cluster sampling method was applied on totally 939 women between 45~ 55 years old collected from three districts in Changchun. The women were assessed with Self Rating Depression Scale (SDS) and Depression Status Inventory (DIS) and the depression symptoms and related biological, psychological and social factors were investigated; 30 examples chosen from group Ⅰ, group Ⅱ, and group Ⅲ between age 25~39, were analyzed on their blood serum estradiol (E 2) level with radiated immune method and case controlled trial. Results:The occurrence rate of depression was 32.06% in climacteric women. The blood serum E 2 levels in group Ⅰ and Ⅱ were lower than that in group Ⅲ, but the serum E 2 level in group Ⅰ was even lower than that in group Ⅱ, there was significant differences; There was a positive correlativity between occurrence of depression and psychological status, blood vessel contraction status,unfortunate events in life, and the ages; There was also a negative correlativity between occurrence of depression, and the monthly family income, employment of the partner, the couple sensation, the satisfaction on life, self evaluation, the time spent on releasing worry, the participation in community organized activities, the help from family or society to release worry.Conclusion:The occurrence of climacteric depression symptom is correlated with the decreasing of E 2 level, and some biological, social, psychological factors. The application of hormone replacement therapy (HRT) can ease the depression symptom in climacteric women. Besides drug therapy, it is also important to have psychological consultation and social supports.
出处
《吉林大学学报（医学版）》
CAS
CSCD
北大核心
2003年第6期847-851,共5页
Journal of Jilin University：Medicine Edition
基金
吉林省卫生厅医学科研基金资助课题 (2 0 0 1 )
