摘要
研究了HIRFL提供的12C6+离子辐照C57BL/6J小鼠右后腿移植的Lewis肿瘤的生长延迟和碳离子辐照对Lewis肿瘤小鼠寿命的延长.结果表明,碳离子照射的小鼠肿瘤生长体积明显地小于对照的体积.在剂量相同、分次数辐照越多时,肿瘤生长就越缓慢,肿瘤抑制就越高.在辐照分次数相同时,不同剂量对受照肿瘤生长体积未产生差异.在4Gy×3,8Gy×3和12Gy×2组3种辐照剂量下,小鼠寿命的P值小于0.05;可知小鼠的寿命延长具有统计学意义.
Growth delay of the transplantable Lewis tumors growing in right hind legs of C(57) BL/6J mice and life prolongation of the mice with Lewis tumors were investigated after()^(12)C^(6+) ion radiation at HIRFL. The results show that growth volumes of the mouse tumors following carbon radiation are distinctly less than control during 21 days; the more fractions of radiation with same doses, the slower growth of tumors and the higher inhibition of tumors; different doses with the same fractions of radiation does not induce difference for growth volume of the irradiated tumors; among 4 Gy×3, 8 Gy×3 and 12 Gy×2 groups P values of the mouse life are less than 0.05 and it indicates that their life prolongation has statistical significance.
出处
《原子核物理评论》
CAS
CSCD
北大核心
2003年第4期281-283,共3页
Nuclear Physics Review
基金
中国科学院院长特别支持基金资助项目(TB990601)~~
