摘要
目的 观察大剂量皮质类固醇对后部间接外伤性视神经病变的治疗效果。方法 对1995年1月～2002年12月住院的41例后部间接外伤性视神经病变,依据就诊时间及治疗方法的不同分为治疗组和对照组,治疗组每天一次静脉滴注地塞米松1 mg/kg·d,连续5天,对照组静脉滴注地塞米松20 mg,连续7天;然后口服强的松40 mg,每3天减10 mg。结果 治疗组26例经治疗视力恢复至0.05以上者22例(84.62％),对照组15例中7例(46.67％)视力达0.05以上,两组间差异具有显著意义(P<0.05),伤后24 h以内就诊治疗者视力恢复情况明显好于24 h以后就诊治疗者(P<0.05)。结论 早期应用大剂量皮质类固醇治疗后部间接外伤性视神经病变效果明显。
Objective To observe the therapeutic efficacy of posterior indirect traumatic optic neuropathy after application of high dosage of corticosteroid. Methods 41 cases of posterior indirect traumatic optic neuropathy diagnosed in our hospital between January 1995 and December 2002 were divided into therapeutic group and control group according to the diagnostic time and treatment methods.The cases in the therapeutic group and in the eontral group were treated by vein dribbling dexamethasone 1 mg/kg·d for five days and 20 mg for seven days respectively and then taken orally prednisone 40 mg stopped application by decreasing 10 mg every three days. Results The visual acuity of 22 (84.62%) cases in the therapeutic group was reached 0.05 or above which was statistically significant contrasted with 7(46.67%) in the control group. The treatment results between less and more than 24 h after trauma was statistically different.Conclusion The visual prognosis of posterior indirect traumatic optic neuropathy can be remarkably improved by earlier application of high dosage of corticosteriod.
出处
《眼外伤职业眼病杂志》
北大核心
2003年第11期752-753,共2页
Journal of Injuries and Occupational Diseases of the Eye with Ophthalmic Surgeries
