摘要
目的 :探讨药疹发生发展的规律。方法 :回顾分析我院皮肤科自 1995年以来收治的住院药疹 2 85例 ,内容包括 :性别、年龄、疹型、致敏药物、潜伏期、药物反应史、并发症、治疗方法及转归。结果 :性别男女之比 1∶1.33。年龄以 4 0～ 4 9岁组最多。药疹类型以荨麻疹型最常见。致敏药物以抗生素及解热镇痛药最常见。潜伏期最长 2 8d ,最短 10min。既往有药物过敏史的病例占 2 9.2 %。药疹合并内脏器官反应的病例占相当比例。 2 84例治愈 ,仅 1例死亡。结论 :近年来药疹类型及致敏药物发生明显变化 ,并发症常见 ,首选激素治疗 。
Objective: To investigate the rules of the occurrence and development of drug eruptions. Methods: 285 drug eruptions inpatients was reviewed retrospectively since 1995. We studied sex,age,eruptive form,allergic drug,incubation period,drug reaction,complication,therapy and prognosis. Results: The proportion of sex was 1∶1.33. The 40～49 year was the most. The form of Urticaria was the most. Antibiotics and antipyretic analgesic was the most common. The longest time of incubation period is 28 days and the shortest was 10 minutes. The cases with drug reaction were 29.2%. There were more cases combined visceral organs reactions. 284 cases was cured and one case was dead. Conclusion: There are apparent changes in drug eruptions forms and allergic drugs. There are more cases with the complications. The first therapy is corticosteroid. The prognosis is good.
出处
《中国临床医学》
2003年第6期845-846,850,共3页
Chinese Journal of Clinical Medicine
