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^(11)C-胆碱和^(18)F-FDG在肿瘤PET中的比较

The comparison of ^(11)C-choline and ^(18)F-FDGin tumor imaging with positron emission tomography
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摘要 11C-胆碱是最近研制的一种正电子肿瘤阳性显像剂,在肿瘤/非靶组织的比值高于18F-FDG,特别在脑肿瘤和前列腺癌显像方面较18F-FDG显示出优势。11C-胆碱和18F-FDG在脑肿瘤、肺癌、食道癌和前列腺癌的诊断方面各有优劣,两者的摄取机理与显像方法也不同。除了11C-胆碱,还有18F-氟代胆碱(18F-fluorocholine),其临床价值有待更多的研究来证实。 s: 11C-choline is a newly developed positron tumor positive imaging agent. In the imaging the T/N (tumor/normal) value is higher than that of 18F-FDG and superior than 18F-FDG especially in brain tumor and prostate cancer detection. 11C-choline and 18F-FDG showed different value in the detection of brain tumor, lung cancer, esophagus cancer and prostate cancer. Their accumulation mechanism and imaging modality was different too. Besides 11C-choline, 18F-fluorocholine was also introduced, its clinical value need more study to prove.
作者 袁志斌 马寄晓
机构地区 上海交通大学医学院上海市第六人民医院核医学科副主任技师 上海市第六人民医院
出处 《国外医学（放射医学核医学分册）》 2003年第6期251-254,共4页 Foreign Medical Sciences(Section of Radiation Medicine and Nuclear Medicine)
关键词 ^18C-胆碱 ^18F-FDG 肿瘤 PET ^18F-氟代胆碱 ^18F-氟代脱氧葡萄糖 诊断 positron emission tomography 11C-choline 18F-fluorodeoxyglucose 18F-fluorocholine comparison study
分类号 R730.4 [医药卫生—肿瘤]
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参考文献12

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国外医学（放射医学核医学分册）
2003年 第6期

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