摘要
乳腺癌的基因治疗是近年来肿瘤治疗研究的热点,目前处于实验或临床初步应用的基因治疗方法主要有免疫基因治疗、多药耐药基因治疗、反义寡核苷酸治疗、自杀基因治疗等方法,而将基因治疗与放射性核素相结合的基因靶向近距离放射治疗的方法具有放射性核素与自杀基因对肿瘤细胞的双重杀灭作用,为肿瘤基因治疗开辟了一条崭新的途径,在这一领域进一步研究必将加快基因靶向治疗向临床应用迈进的步伐。
Breast carcinorma's gene therapy is a hotspot in study of the tumor's therapy in the recent years. Currently the major therapy methods that in the experimentative and primary clinical application phases include immunological gene therapy, multidrug rssistrance gene therapy, antisense oligonucleotide therapy and suicide gene therapy. The gene targeting brachytherapy, which is combined with gene therapy and radiotherapy has enhanced the killer effects of the suicide gene and nuclide in tumor cells. That has break a new path in tumor's gene therapy. The further study in this field will step up it's space to the clinical application.
出处
《国外医学（放射医学核医学分册）》
2003年第6期241-244,共4页
Foreign Medical Sciences(Section of Radiation Medicine and Nuclear Medicine)
基金
国家自然科学基金资助项目(30070229)
