摘要
非小细胞肺癌 (NSCLC)是常见的恶性肿瘤 ,治疗效果不佳 ,有许多术中证实淋巴结阴性的患者仍在术后出现复发 ,这可能是由于存在常规病理手段无法发现的微转移病灶所导致。近年来 ,免疫组化和分子生物学方法已应用于外周血、骨髓及肿瘤附近淋巴结中微转移灶的检测 ,但是检测微转移灶的指标选择及临床意义目前仍有争论。作者讨论常见的检测NSCLC微转移的方法及检测结果的临床意义。
Non-small cell lung cancer has a poor prognosis. Many patients who were proved to have none lymph node metastasis still relapse after operation. It may be caused by micrometastases which can′t be detected by conventional pathologic technique. Recently immunocytochemistry and moleculer methods are used to detect micrometastases in the peripheral blood, bone marrow or lymph node near the tumor. But the standard and reliable methods need to be developed and the clinical significance of micrometastases need to be discussed.
出处
《医学研究生学报》
CAS
2004年第1期73-74,77,共3页
Journal of Medical Postgraduates
