摘要
目的 :探讨血浆C反应蛋白 (CRP)与急性冠脉综合证 (ACS)冠脉病变之间的关系。方法 :测定正常人 (n =5 2 )及不稳定心绞痛 (USA ,n =83)和急性心肌梗死 (AMI,n =4 2 )患者血浆CRP浓度 ,分析冠状动脉病变程度、病变支数及病变类型与相应CRP浓度的关系。结果 :CRP浓度在正常组、USA及AMI组依次增高 ,分别为 ( 3 11±1 82 )mg/L ,( 12 2 0± 5 86 )mg/L和 ( 18 90± 8 96 )mg/L ,P <0 0 1。在ACS组中 ,轻度狭窄、中度狭窄及重度狭窄 ,其CRP浓度也依次增高 ,分别为 ( 6 0 2± 2 18)mg/L ,( 10 0 4± 2 87)mg/L和 ( 18 2 2± 7 6 ) 1mg/L ,P <0 0 1;单支病变、双支病变以及三支病变 ,其CRP浓度依次增高 ,分别为 ( 11 75± 5 33)mg/L ,( 16 86± 5 6 0 0 )mg/L和 ( 2 2 4 1±10 2 5 )mg/L ,P <0 0 1;A型病变、B型病变和C型病变 ,其CRP浓度依次增高 ,分别为 ( 8 2 4± 3 78)mg/L ,( 14 2 1± 4 30 )mg/L和 2 2 4 0± 8 32mg/L ,P <0 0 1。结论 :CRP浓度与冠脉病变程度关联密切。
Objective:To explore the relation of C reaction protein (CRP) to pathological changes of coronary vessels. Methods:CRP contents in 52 normal people, 83 patients with unstable angina pectoris (USA) and 42 patients with acute myocardial infarction (AMI) were all detected to analyze the relation of pathological degree of coronary vessels, numbers and types of pathological vessels to corresponding CRP content. Results:CRP contents in normal, USA and AMI group were 3 11±1 82 mg/L, 12 20±5 86 mg/L, 18 90±8 96 mg/L, respectively (P<0 01). CRP contents in 1 ,2 ,and 3 pathological vessel group were 11 75±5 33 mg/L,18 86±5 00 mg/L and 22 41±10 25 mg/L, respectively (P<0 01); and that in type A, B and C pathological changes group were 8 24±3 78 mg/L, 14 21±4 30 mg/L and 22 40±8 32 mg/L, respectively (P<0 01). Conclusion: CRP content is closely associated with pathological degree of coronary vessels.
出处
《西南国防医药》
CAS
2003年第6期586-588,共3页
Medical Journal of National Defending Forces in Southwest China
