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慢性冠状动脉闭塞病变介入治疗后左室收缩功能的变化 被引量:1

Effects of successful recanalization of chronic coronary occlusions on left ventricular contractility
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摘要 目的 探讨慢性冠状动脉闭塞病变介入治疗后对患者左心室射血功能、室壁运动的影响。方法 83例慢性闭塞病变的患者[平均闭塞时间(4.6±11)个月]因心绞痛行介入治疗,其中支架置入率为74.7%。介入治疗前以及术后(6.9±2.2)个月行超声心动图检查。超声测定左心室射血分数,评价左室局部室壁运动。结果左心室射血分数由治疗前57.3%±14%提高至随诊时的63.4%±11%(P<0.01)。患者左心室室壁运动以及心绞痛在成功进行介入治疗后有明显改善。结论 介入治疗可使闭塞冠状动脉开放,从而明显提高左心室的射血功能,改善缺血心肌的室壁运动。 Objective To assess changes in left ventricular ejection fraction and regional wall motion after successful angioplasty of chronic coronary occlusions. Methods In eighty three patients with angina pectoris with a successful re-canalized chronic coronary occlusion(median duration 4.6 months) ,echocardiography were obtained at baseline and (6.9 ± 2.2)months later. Left ventricular ejection fraction and regional wall motion were evaluated by echocardiography. Results Successful rate of chronic total occlusion is 79. 8% (83/104). Left ventricular ejection fraction increased from 57.3%±14% at baseline to 63.4%±11% at follow-up (P<0.01)after successful angioplasty. Hypokinesis and akine-sis segments significantly decreased from 78 and 20 at baseline to 52 and 17 at follow-up respectively. It indicated that regional wall motion was improved. Conclusions Recanalization of chronic coronary occlusion in patients with angina pectoris is associated with improvement in global and regional left ventricular function. This may be a result of recovery of hibernating myocardium and supports the strategy of recanalization of chronic coronary occlusions.
出处 《北京医学》 CAS 北大核心 2003年第6期369-371,共3页 Beijing Medical Journal
关键词 慢性闭塞病变 支架 冬眠心肌 慢性冠状动脉 左心室射血 Chronic total occlusion Angioplasty Hibernating myocardium
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