摘要
目的 为探讨乙型病毒性肝炎HBsAg弱阳性的检测及其临床意义。方法 对ELISA法检测的 80例患者HBsAg弱阳性标本行乙肝“三对半”检测 ,方法有 6种模式。结果 PCR检测 5例为阳性 ,阳性率为 6.2 % ,CIC阳性 2 7例 ,阳性率为 3 3 .7%。测定管与对照管的吸光度比值为 2 .91± 1.42 ,同时已测定了相应血清的ALT、AST、GGT分别为 12 .3 4± 5 .5 9U/L、11.5 2± 6.3 5U/L及 14 .3 4± 3 .2 5U/L。结论 产生HBsAg弱阳性的现象可能是患者的免疫功能受损后 ,机体与HBV或其应答产物产生新的免疫平衡的反应 ,一般情况下不具严重的致病性 ,但在重新受到HBV的严重感染下 ,可能被激发而导致病情加重 。
Objective To evaluate the examination of weak positive HBsAg in hepatitis B virus (HBV).Methods Fasting blood of 80 patients with weak positive HBsAg of HBV were collected and serum were measured on day by ELISA,PCR,the examinaftion of CIC(circle immune complex).Results Among the 80 patients,the positive number of PCR,CIC were 5,27 respectively.Conclusion In caes of decline of immune fanction and the serve infection of HBV or subtypes in HBV,the situations of the patients may become worse or suffer from cancers.
出处
《右江医学》
2003年第6期542-543,共2页
Chinese Youjiang Medical Journal
