摘要
目的:观察纳洛酮与传统药物治疗急性重度酒精中毒时的疗效。方法:将2001年1月至2003年1月间收治的108例急性重度酒精中毒患者随机分为55例纳洛酮治疗组(治疗组)与53例常规药物治疗组(对照组),观察和比较两组患者的清醒时间和住院时间。治疗组在对照组的基础上首剂用纳洛酮0.8 mg静注,以后每隔30-45 min再0.4 mg静注,直至患者清醒、症状消失为止。结果:治疗组病人平均清醒时间和住院时间分别为4.8 h和6.5 h,较对照组的11.6 h和17.4 h均明显缩短(P<0.01)。结论:纳洛酮治疗急性重度酒精中毒催醒效果好,住院时间短,安全性高。
Objective: To observe the efficacy of Nalaxone with the traditional medicine in treating the patients with acute severe alcoholism. Methods: 108 cases divided into Nalaxone treated group (treating group, n=55) and the traditional medicine group (control group, n=53) randomly. Observing and analysis the weaken time and in hospital time of the two groups. On the basic of the traditional medicine, the treating group was added to Nalaxone by 0.8 mg iv first and followed 0.4 mg per 30~40 min until the symptoms disappearing. Results: The average time both weaken and in hospital in treating group were shorter than the control group(4.8&11.6 hours,6.5&17.4 hours) significantly(P< 0.01). Conclusion: Using Nalaxone treat the acute severe alcoholism may short the weaken time and in hospital time and safety.
出处
《岭南急诊医学杂志》
2003年第4期282-283,共2页
Lingnan Journal of Emergency Medicine
