摘要
目的 :观察和评价含可乐必妥化疗方案治疗难治性肺结核的疗效及安全性。方法 :将符合选择条件的 72例难治性肺结核患者随机分为治疗组 ( 38例 )和对照组 ( 34例 ) ,分别用含可乐必妥化疗方案与不含可乐必妥化疗方案进行治疗 ,对两组疗效进行对照分析。结果 :满疗程时治疗组、对照组分别有 35例、30例 ,治疗组痰菌阴转率 85 .7% ,病灶吸收好转率 91 .4% ,空洞闭合好转率 77.1 % ,均明显高于对照组相应指标 5 3.3% ( P<0 .0 0 5 ) ,66.7% ( P<0 .0 5 ) ,5 3.4% ( P<0 .0 5 ) ,未见明显毒、副作用。结论 :含可乐必妥的化疗方案治疗难治性肺结核病安全、疗效好、副作用少 ,组合方案合理 。
Objective:To observe and evaluate the therapeutic effect security of Levofloxacin in treating the patients with refractory pulmonary tuberculosis. Methods:72 cases who had experienced refractory pulmonary tuberculosis were group into trial group(using Levofloxacin )and control group(no Levofloxacin),and then the therapeutic effect were analyzed and evaluated by clinical observation.Results:When the treatment trial have been accomplished, 35 cases in trial group and 30 in control group could be used into this study.The rate of the sputum negative conversion,focal absorption and the cavity vanishing were 85.7%,91.4%and 77.1% respectively,which were significantly higher than that in control group(53.0%,66.7%and 53.4%),P<0.05.Moreover,clinical observation showed that this treatment did not have significant side effect. Conclusion:The therapeutic scneme have satisfactory therapeutic effect and low risk ,and it is worth to practice clinically.
出处
《陕西医学杂志》
CAS
北大核心
2004年第1期67-69,共3页
Shaanxi Medical Journal
关键词
可乐必妥
化疗方案
治疗
难治性肺结核
安全性
左旋氧氟沙星
Tuberculosis, pulmonary/diagnose Tuberculosis, pulmonary/drug therapy Ketone/therapeutic use
