摘要
目的 探讨青年人结直肠癌的临床及病理特点。方法 回顾分析我院 1980～ 2 0 0 0年 2 0年间行手术治疗 ,并经病理检查确诊的结直肠癌年轻患者 14 3例 (占同期收治结直肠癌的 13.9% )的临床资料。将所有病例以年龄为界划分为 4组 :<35岁组 ,35岁～组 ,5 0岁～组 ,6 5岁～组。对 <35岁青年人结直肠癌与各组进行比较。结果 青年人结直肠癌的构成比男性高于女性 ,临床分型以浸润型和胶样型为主 ,分别占 5 6 .6 %和 31.5 % ;组织病理学类型以低分化腺癌 (37.8% )、粘液腺癌 (2 9.6 % )为多 ,89.5 %的病例Dukes临床分期为B期和C期。结论 临床晚期结直肠癌病例多及病理组织学分化差是青年人结直肠癌预后差的重要原因 ,应提高对青年人结直肠癌的认识 ,做到早期诊断、早期治疗 ,这是提高疗效的关键。
Objective To analyse the clinico-pathological characteristics of young patients with colorectal cancer. Methods From January 1980 to January 2000, among 1 030 patients with colorectal cancer admitted for surgical treatment, 143 (13.9%) patients were <35 years of age. The clinico-pathological data of these young patients were reviewed and compared with those of patients in the other age groups. Results In this series of young patients, males were predominat. Most of them were with poorly differentiated (37.8%) and muco-cellular (29.6%) adenocarcinoma. The mast common gross morphology was infiltrating type (56.6%) and colloid carcinoma type (31.5%). The majority of patients (89.5%) were in Dukes stage B and stage C.Conclusion The prognosis of young patients with colorectal cancer surgically treated is worse, due to the fact that most of them are in late stage and their cancers are worse in differentiation. To increase the awareness of cancer in the young is important for early diagnosis and treatment and better prognosis.
出处
《中国普外基础与临床杂志》
CAS
2004年第1期52-54,共3页
Chinese Journal of Bases and Clinics In General Surgery
关键词
青年人
病理
结肠癌
直肠癌
诊断
治疗
Colon cancer Rectum cancer Pathology Diagnosis Therapy
