摘要
Chiral sulfonamides derived from(d)-10-camphorsulfonyl chloride and chiral amines were prepared and used in the copper-catalyzed conjugate addition of organometallic reagents to enones.The chiral sulfonamides/CuCN catalysts provided high catalytic activity and moderate enantioselectivity in the conjugate addition of diethylzinc to 2-cyclohexenone and 2-cyclohepteneone,but low enantioselectivity to the 2-cyclopentenone and acyclic enones.
Chiral sulfonamides derived from(d)-10-camphorsulfonyl chloride and chiral amines were prepared and used in the copper-catalyzed conjugate addition of organometallic reagents to enones.The chiral sulfonamides/CuCN catalysts provided high catalytic activity and moderate enantioselectivity in the conjugate addition of diethylzinc to 2-cyclohexenone and 2-cyclohepteneone,but low enantioselectivity to the 2-cyclopentenone and acyclic enones.
出处
《化学研究与应用》
CAS
CSCD
北大核心
2003年第6期886-888,共3页
Chemical Research and Application
基金
香港研究资助局项目(PolyU34/96P)
苏州大学科研启动基金资助项目(Q4109308)
