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抑肽酶应用的临床进展 被引量:3

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摘要 抑肽酶是从牛肺中提取的丝氨酸蛋白酶抑制剂,它主要抑制纤溶酶,广泛用于心肺转流(CPB)心脏手术中,以减少术中、术后出血,现也应用于非心脏大手术如骨科大手术和肝脏移植手术.因纤溶酶对血小板数量和功能有破坏作用,抑肽酶对血小板也具保护作用,抑肽酶能抑制中性白细胞激活和脱颗粒,减少补体激活,具有抗炎作用而进一步受到临床的重视[1].
作者 邓硕曾
出处 《临床麻醉学杂志》 CAS CSCD 2003年第11期705-706,共2页 Journal of Clinical Anesthesiology
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参考文献11

  • 1邓硕曾.新世纪血液保护的展望[J].临床麻醉学杂志,2001,17(6):349-351. 被引量:43
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二级参考文献7

共引文献83

同被引文献28

  • 1邓硕曾,杜磊.抑肽酶有抗炎作用吗?[J].临床麻醉学杂志,2004,20(9):570-571. 被引量:2
  • 2曹忠平,陶国才,刘怀琼,鲁开智,崔剑.抑肽酶对肝缺血再灌注过程中兔血小板功能的影响[J].中华麻醉学杂志,2004,24(10):779-780. 被引量:2
  • 3Alvarez JM,Jackson LR,Chatwin C.Low-dose postoperative aprotinin reduces mediastinal drainage and blood product use in patients undergoing primary coronary artery bypass grafting who are taking aspirin:aprospective,randomized,double-blind,placebo-controlled trial[J].J Cardiothorac Vasc Anesth,2001; 15:326-330.
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