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颅内生殖细胞瘤的诊断及综合治疗 被引量:1

Diagnosis and Treatment of Intracranial Germinoma
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摘要 目的探讨颅内生殖细胞瘤的诊断及综合治疗方法与疗效。方法本组颅内生殖细胞瘤31例中,29例手术治疗(含1例行脑室-腹腔分流,3例行脑室外引流),2例未手术。此外,29例进行了放疗,8例进行了化疗。结果临床症状改善27例,无变化4例。随访27例,13例恢复正常工作;8例生活能自理;2例生活需要帮助;2例术后2年复发,经再次手术,症状缓解;死亡2例。结论颅内生殖细胞瘤手术难以根治,术后正规放疗效果好,对多发性,复发性肿瘤可放疗加化疗。 Objective To investigate the clinical characteristics,and diagnosis and treatment methods of intracranial germinoma.Method Of31paients with intracranial germinoma,29were surgically treated(including1receiving ventriculopperitoneal shunt and3extraven-tricular drain)and2did not undergo the surgery.The radiotherapy was performed in29patients and chemotherapy in8.Results Of31patients,27improved in clinical symptoms and4were unchanged.Of27patients followed up,13returned to their work,8could take care of themselves and2not,2underwent reoperation on for the recurrent tumor and2died.Conclusions It is difficult to cure intracranial germinoma thorou-ghly.The radiotherapy can satisfactorily improve patient's prognosis after the operation.The multiple or recurrent tumors should be treated by chemiotherapy after the operation.
出处 《中国临床神经外科杂志》 2003年第6期432-434,共3页 Chinese Journal of Clinical Neurosurgery
关键词 颅内生殖细胞瘤 诊断 治疗 Intracranial germinoma Diagnosis Treatment
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二级参考文献2

  • 1罗世祺,儿童颅内肿瘤,1992年,249页
  • 2罗世祺,Surg Neurol,1989年,32卷,36页

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  • 1Bamberg M, Kortmann RD, Calaminus G, et al. Radiation therapy for intracranial germinoma: results of the german cooperative prospective trials MAKEI 83/86/89. J Clin Oncol, 1999, 17(8):2585-2592.
  • 2Shibamoto Y, Takahashi M, Sasai K. Prognosis of intracranial germinoma with syncytiotrophoblastic giant cells treated by radiation therapy. Int J Radlat Oncol Biol Phys, 1997, 37 (3): 505-510.
  • 3Yoshida J, Sugita K, Kobayashi T, et al. Prognosis of intracranial germ cell tumottrs: Effectiveness of chemotherapy with cisplatin and etoposide (CDDP and VP-16). Acta Neurochir (Wien), 1993,120 (1): 111-117.
  • 4Aoyama H, Shirato H, Ikeda J, et al. Induction chemotherapy followed by low-dose involved-field radiotherapy for intracranial germ cell tumors. J Clin Oneol, 2002, 20 (3): 857-865.
  • 5Shin KH, Kim IH, Choe G. Impacts of elevated level of hCG in serum on clinical course and radiotherapy results in the histology-confirmed intracranial germinomas. Acta Oncol, 2001, 40(1): 98-101.
  • 6Ogawa K, Shikama N, Toita T, et al. long-term results of radiotherapy for intracranial germinoma: a multi-institutional restrospective review of 126 patients, Int J Radiat Oncol Biol Phys,2004, 58 (3): 705-713.
  • 7Aoyama H, Shirato H, Kakuto Y, et al. Pathologically-proven intracranial germinoma treated with radiation therapy. Radiother Oncol, 1998, 47 (2): 201-205.
  • 8Shibamoto Y, Sasai K, Oya N, et al. Intracranial germinoma:Radiation therapy with tumor volume-based dose selection.Radiology, 2001, 218(2): 452-456.
  • 9Matsutani M, Sano K, Takakura K, et al. Primary intracranial germ cell tumors: A clinical analysis of 153 histologically verified cases.J Neurosurg, 1997, 86(2): 446-455.
  • 10Merchant TE, Goloubeva O, Pritehard DL, et al. Radiation dosevolume effects on growth hormone secretion. Int J Radiat Oncol Biol Phys, 2002, 52(5): 1264-1270.

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