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survivin与消化系统肿瘤 被引量:1

Relation of survivin with digastive tract tumor
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摘要 survivin是凋亡抑制蛋白 (IAP)家族的一个新成员 ,具有抑制细胞凋亡的作用。研究表明 ,sur vivin在消化系统肿瘤的广泛特异性表达与肿瘤进程和预后明显相关 ,并可能是导致肿瘤细胞耐药性的因素。同时 ,survivin为肿瘤的早期诊断和基因治疗、免疫治疗提供了新的广阔前景。
出处 《中国普通外科杂志》 CAS CSCD 2003年第11期855-857,共3页 China Journal of General Surgery
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同被引文献5

  • 1段体德,刘德权,杨策尧.Survivin反义寡核苷酸对乳腺癌荷瘤裸鼠的抑瘤作用研究[J].中国普通外科杂志,2005,14(9):691-695. 被引量:8
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  • 3ShinS,SungBJ,ChoYS,et al.An anti-apoptotic protein human Survivin is a direct inhibitor of caspase-3 and caspase -7[J].Biochemistry,2001,40(4):1117-1123.
  • 4VerdeciaMA,HuanH,DutilE,et al.Structure of the human antiapoptotic protein survivin reveals a dimeric arrange ment[J].NatStructBiol,2000,7(7):602-608.
  • 5龙厚勇,郑启昌.RNAi的作用机制及其应用[J].国外医学(分子生物学分册),2003,25(5):267-270. 被引量:3

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