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新生儿经皮胆红素测定的应用探讨

Application of Transcutaneous Bilirubin Measurements in Newborns
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摘要 目的:评估足月新生儿及早产儿经皮胆红素(TcB)测定的临床应用价值。方法:测定39例足月儿、13例早产儿的血清总胆红素值及额部、胸骨处的TcB读数,并对两者作直线相关分析。结果:足月儿的TcB读数与血清总胆红素值显著相关(r=0.886,P<0.001),而早产儿两者之间无显著相关(r=0.221,P>0.25);足月儿额部、胸骨中部TcB测定的重复性相近。结论:足月儿可依额部或胸骨中部TcB读数推算出血清总胆红素值,但该值与TcB测定仪提供的数值差别较大。各实验室应建立自己的TcB读数与血清总胆红素值之间的对应关系。TcB测定应用于监测早产儿高胆红素血症时应慎重。 Objective: To evaluate the clinical values of transcutaneous bilirubin(TcB) measurements in fullterm infants and in premature neonates. Methods: Transcutaneous bilirubin(TcB) measurements and total serum bilirubin determinations were performed in 39 fullterm infants and 13 premature infants and the data were submitted for linear correlation analysis. Results: TcB reading was correlated well with serum bilirubin level in fullterm infants(r=0.886,P<0.001),but not in premature neonates(r=0.21,P>0.25).The repeating of TcB tests on the forehead and on the midsternum was similar(2=0.81,P>0.05). Conclusion: The serum bilirubin values can be computed from TcB reading according to our regression,However,those values are different from the values suggested by the company of TcB meter.It is important to recognize that each institution should establish its own criteria for the use of this instrument and that TcB measurements can hardly be recommended for the indentification of hyperbilirubinemia in premature infants.
出处 《浙江大学学报(医学版)》 CAS CSCD 1999年第3期134-136,共3页 Journal of Zhejiang University(Medical Sciences)
关键词 新生儿 胆红素 测定 早产儿 血清 Bilirubin/anal Infant newborn
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