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控制性降压在鼻窦内窥镜手术中的临床研究

Clinical Study of Controlled Hypotension in Endoscopic Sinus Surgery
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摘要 目的 :观察控制性降压在鼻窦内窥镜手术 (FESS)中应用效果。方法 :将 6 0例患者随机分为 3组 ,每组 2 0例 ;I组为对照组不实施控制性降压 ; 组为硝酸甘油 (NTG)控制性降压 ; 组为美托洛尔复合 NTG控制性降压。观察比较3组术中出血量、尿量及手术时间。结果 :I组与 、 组比较手术时间延长 (P<0 .0 5 ) ;术中出血量 、 组都显著小于 I组 (P<0 .0 1 ) ;术中 组心率明显比正常心率快 (P<0 .0 5 )。结论 :美托洛尔复合 NTG降压有明显的协同作用 ,减少 FESS术中出血量 ,且手术时间较短 ,对心率影响小 。 Objective:To observe the effect induced by controlled hypotension in endoscopic sinus surgery.Methods:60 patients were randomly divided into three groups.Group I:control group( n =20);Group Ⅱ:nitroglycerin group( n =20);Group Ⅲ:metoprolol and nitroglycerin group( n =20).Amount of blood loss and urine,time of operation were observed and compared among the tree groups druring the operation.Results:Time of operation in group I was increased as compared with that of group Ⅱ and Ⅲ( P <0.05).Amount of bleeding in group I was also increased ( P <0.01).Heart rate in group Ⅱ was increased significantly during operation.Conclusion:Metoprolol combined with NTG produces synergism,time of operation and amount of blood loss decreased,slight influence on HR,and it can safely applied to the controlled hypotension in clinical practice.
作者 庾俊雄
出处 《华夏医学》 2003年第6期785-786,共2页 Acta Medicinae Sinica
关键词 内窥镜术 降压 手术 endoscopy hypotension operation
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