摘要
本文分析了线虫和酵母基因组中1-3核苷酸的串联重复序列,对比这样的序列在内含子、外显子和基因间区域的分布情况,发现不同的重复模式在不同区域的重复特点各不相同,尤其是三核苷的重复在编码区和非编码区中的分布有显著的差异,在外显子中AAG模式的重复占优势,在内含子和基因间序列中AAT模式的重复占优势,CCG模式的重复在任何序列中均罕见.
Tandem sequence repeats prevail in eukaryotic g enomes.A study of the repeat sequences helps to reveal the regulation and control mechanism of the expression of biological genes on the higher level.A comparison has been made of the distribution of repeat sequences in,respectively,introns,extons and intergenic regions of c-elegans and yeast genomes.It is found that different repetitive patterns demonstrate characteristic differences in different regions.Particularly,significant difference has been observed in the distribution of trinucleotide repeats in protein coding and non-coding regions.The repeats of AAG motif have greater preponderance in extons;the repeats of AAT motif have greater preponderance in introns and intergenic regions;while the repeats of CCG motif can rarely be detected in any of the sequences.
出处
《内蒙古工业大学学报（自然科学版）》
2003年第1期12-15,共4页
Journal of Inner Mongolia University of Technology：Natural Science Edition
基金
校基金资助项目(200218)
关键词
串联重复
三核苷酸
外显子
tandem sequence repeats
trinucleotide
exton
