摘要
随着妇女平均寿命的延长 ,绝经后的问题日益受到全社会的广泛关注 ,旨在改善妇女生活质量的激素替代治疗(HRT)所引发的问题也不断涌现。 2 0 0 2年 7月 ,美国国立卫生研究院心脏、肺和血液研究所宣布 ,妇女健康初始行动 (WHI)在健康绝经后妇女中使用雌激素加孕激素的临床试验由于乳腺癌发病相对风险增加 2 6 % ,且并无总体益处予以提前终止。在上述对HRT弊端新认识的背景下 ,中医中药面临着前所未有的走向世界的新契机。大量临床和实验研究证明 ,中医中药对更年期综合征引起的各种症状有较好的治疗效果 ,而且副作用少 ,因此中医辨证治疗有望替代或补充雌激素疗法对更年期综合征的治疗作用 ,最大限度地减少完全用雌激素替代治疗所引起的副作用。
In July 2002, the Women's Heath Initiative (WHI) clinical trial, designed to clarify the risks and benefits of combination hormone replacement therapy (HRT) to the postmenopausal women declared that interim safety review after an average follow up of 5.2 years found that a combination of estrogen and progestin frequently prescribed to postmenopausal women in USA increased the risk of invasive breast cancer, heart disease, stroke, and pulmonary embolism while reduced bone fractures and colorectal cancer. The overall risks of HRT outweigh the benefits, which provides an opportunity for traditional Chinese medicine (TCM) going abroad. A variety of clinical and experimental evidences have showed that TCM exerts quite satisfactory effect on relieving postmenopausal symptoms with little adverse effect, hence a potential role to replace or to improve HRT or to reduce the side effect induced by HRT.
出处
《中西医结合学报》
CAS
2003年第1期9-11,共3页
Journal of Chinese Integrative Medicine
