摘要
目的:分析直肠癌术后放疗的疗效及预后因素.方法:1983年1月～1992年12月收治直肠癌术后放疗216例.采用^(60)CO或15MV X线外照射,剂量DT13.6～80Gy,DT45Gy以上采用缩野技术,疗程9～147天.前后野剂量比大多数为1:2.结果:总的5年生存率为33.8%(73/216).10年生存率为8.8%(19/216).术后放疗组5年生存率为51.5%(68/132),复发后放疗5年生存率为6.0%(5/84),两者差异有显著意义(P<0.05).其中156例已死亡病例中术后放疗与复发后放疗死于局部复发或复发未控制分别为34.4%与66.7%,死于血行转移分别为65.6%与33.3%,有显著差异.结论:C期直肠癌术后应常规行术后放疗,适宜剂量DT45～60Gy,疗程直<50天.复发患者应及时确诊,尽早放疗,剂量充足.
Objective: to analyse the therapeutic effectiveness and prognostic factors of postoperative radiotherapy. Methods:216 postoperative patients with rectal carcinoma were treated from 1983.1 to 1992.12. 60CO or 15MV Xray was used. Tumor dose of radiation was between 13.6Gy-80Gy. If tumor dose was over 45Gy, the technique of boost was used. Overall course was 9-147 days. Anteroposterior dose ratio was 1:2 mostly.Results:Overall 5 - year and 10- year survival rate was 33.8% (73/216) and 8.8% (19/216), respectively. 5-year survival rate between postoperative radiotherapy (51.5%) and radiotherapy of postoperative relapse 6.0% has statisticd difference (P<0.05) .Among 156 died patients, groups of postoperative radiotherapy and postoperative relapse occupied 34.4 % and 66.7% respectively. The percentage of the two groups which died of distant matastasis were 65.6% and 33.3 % respectively. The two group has obvious difference. Conclusions postoperative radiotherapy must give the patients who have been operated. Optimal dose is DT45-60Gy and treatment period is below 50 days. Recurrent patients must be diagnosed in time and radiated as soon as possible. Radiation dose must be sufficient.
出处
《临床肿瘤学杂志》
CAS
1999年第4期7-9,共3页
Chinese Clinical Oncology
关键词
直肠癌
手术
放疗
死亡率
生存率
疗效
Rectal carcinoma Postoperative Radiotherapy Prognosis.
