摘要
目的 研究环境因素对磷酸钛钠抗菌剂的抗菌活性的影响。方法 利用摇瓶法测定大肠杆菌ATCC4 4 113在各种环境条件下培养后的存活菌数。结果 在试验细菌浓度为 (1 2× 10 2 )～(1 2× 10 8)cfu/ml的范围内 ,存活菌数随试验细菌浓度的提高而增大 ;抗菌剂抗菌活性在 16～ 4 6℃的范围内随温度的升高而增强 ;共存NaCl和蛋白质使抗菌剂抗菌活性下降 ,但分别在浓度为 0 0 1g/ml和 0 0 0 0 5g/ml处达到饱和值 ,超过此值时 ,抗菌性能不再下降。结论 在细菌浓度较大的场合 ,利用该抗菌剂所做成的抗菌材料必须和有机抗菌剂同时使用才能得到良好的洁净环境效果 。
Objective To investigate the effects of ambient conditions on the antibacterial activity of inorganic antibacterial agent based on sodium titanium phosphate Methods The number of live E Coli ATCC 44113 was counted after the suspension was shaken and incubated in flask with antibacterial agent under ambient conditions Result The number of live bacteria increased when the concentration of bacteria increased in the range of 1 2×10 2 to 1 2×10 8 cfu/ml The antibacterial activity increased with the increase of ambient temperature in the range of 16～46 ℃,showing good antibacterial activity at human body temperature With the increase of the concentrations of co existing NaCl and protein, the antibacterial activity was found to decrease at first and level off at 0 01 g/ml and 0 000 5 g/ml respectively Conclusion The antibacterial agent has to be used together with organic antibacterial agent in order to achieve good antibacterial effect when the ambient bacterial concentration is high The antibacterial agent is promising to be used in the preparation of antibacterial cloth because it is highly effective at body temperature and expected to remain antibacterial in perspiration.
出处
《中华预防医学杂志》
CAS
CSCD
北大核心
2002年第2期114-116,共3页
Chinese Journal of Preventive Medicine
