摘要
目的:探讨抗菌药物在临床的合理应用。方法:随机抽取1998年6月～12月出院病案143份(例),进行分析。结果:其中应用抗菌药物132例(92.3％)。132例中,用于治疗69例(52.3％),用于预防63例(47.7％)。细菌培养标本16份,培养阳性率31.5％。应用抗菌药物10大类43种1573用药日。不合理应用比例分别为39.4％(按例数算)及42.5％(按用药天数算)。不合理应用的主要原因是:非适应证用药和预防用药时间过长。结论:调查结果提示:①应及早制订本单位抗菌药物临床应用规范并认真贯彻执行。②强化临床医师合理应用抗菌药物的意识。③充分利用实验室条件进行细菌培养和药敏试验,以提高诊治水平。
Objective: To check if antibacterials were rational in clinical use. Methods: 143 inpatients between June and December 1998 were enrolled for retrospective analysis of drug administration. Results: 132 cases took antibacterial drugs accounting for 92.3% , among them 69 cases (52.3%) for treatment and 63 cases (47.7%) for preventive purposes. From the said patients only 16 samples were collected and sent for bacterial culture, its positive rate being 31.5% . Antibacterials taken covered 43 kinds of 10 categories, altogether 1573 drug-days. The rate of the unreasonable application was 39.4% (52/132 cases) or 42.5% (668/1573 drug-days) . Medication for wrong indications or for a longer period than neccessity could be the main problem. Conclusion: In order to upgrade the diagnostic and therapeutic level, medical professionals should have knowledge of and be familiar with antibacterials and use them in a reasonable way in combination with bacterial culture and drug sensitivity test, if possible.
出处
《药物不良反应杂志》
2000年第3期159-164,共6页
Adverse Drug Reactions Journal
